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A
for
B
with
C
about
D
to
正确答案 :A
解析
本题考查英语词法——介词。
句意“吸烟是导致肺癌死亡的主要原因。”be responsible for…“形成……的原因,对……负责”,固定搭配,A 项符合题意。
B项: with "和……一起"。不符合题意,故排除。
C项: about "大约"。不符合题意,故排除。
D项:to "向",其后接表对象的人或物。不符合题意,故排除。
故本题答案为A。
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